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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MET
All Species:
9.09
Human Site:
S1197
Identified Species:
25
UniProt:
P08581
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08581
NP_000236.2
1390
155541
S1197
K
G
M
K
Y
L
A
S
K
K
F
V
H
R
D
Chimpanzee
Pan troglodytes
Q2QLF1
1390
155551
S1197
K
G
M
K
Y
L
A
S
K
K
F
V
H
R
D
Rhesus Macaque
Macaca mulatta
NP_001162100
1381
154449
L1195
V
A
K
G
M
K
Y
L
A
S
K
K
F
V
H
Dog
Lupus familis
XP_533823
1410
153277
E1211
R
G
M
E
Y
L
A
E
Q
K
F
V
H
R
D
Cat
Felis silvestris
Mouse
Mus musculus
P16056
1379
153530
L1193
V
A
K
G
M
K
Y
L
A
S
K
K
F
V
H
Rat
Rattus norvegicus
P97523
1382
153923
L1196
V
A
K
G
M
K
Y
L
V
S
K
K
F
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07E01
1382
154611
L1196
V
A
K
G
M
K
Y
L
A
S
K
K
F
V
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001163830
1425
157559
S1215
R
G
M
E
Y
L
A
S
K
K
F
V
H
R
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190267
1321
146315
A1135
D
P
S
N
E
L
T
A
R
Q
L
L
E
F
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
35.1
N.A.
88.8
87.7
N.A.
77.3
N.A.
N.A.
N.A.
48.4
N.A.
N.A.
N.A.
28.7
Protein Similarity:
100
99.8
98.7
52.2
N.A.
94.4
93.5
N.A.
86.6
N.A.
N.A.
N.A.
66
N.A.
N.A.
N.A.
48.9
P-Site Identity:
100
100
0
73.3
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
0
93.3
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
45
0
0
0
0
45
12
34
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% D
% Glu:
0
0
0
23
12
0
0
12
0
0
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
45
0
45
12
0
% F
% Gly:
0
45
0
45
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
45
0
45
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
23
0
45
23
0
45
0
0
34
45
45
45
0
0
0
% K
% Leu:
0
0
0
0
0
56
0
45
0
0
12
12
0
0
0
% L
% Met:
0
0
45
0
45
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% Q
% Arg:
23
0
0
0
0
0
0
0
12
0
0
0
0
45
0
% R
% Ser:
0
0
12
0
0
0
0
34
0
45
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% T
% Val:
45
0
0
0
0
0
0
0
12
0
0
45
0
45
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
45
0
45
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _